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Diethyl chlorophosphate → 1-[Ethoxy(isothiocyanato)phosphoryl]oxyethane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diethyl chlorophosphate | HCID 13139 | — |
| 反応物 | Ammonium thiocyanate | HCID 15666 | — |
| 反応物 | Sodium | HCID 5360545 | — |
| 反応物 | Potassium | HCID 5462222 | — |
| 生成物 | 1-[Ethoxy(isothiocyanato)phosphoryl]oxyethane | HCID 556832 | — |
反応手順
One molar equivalent of diethoxyphosphoryl chloride of formula (II) is reacted with 1.0 to 1.2 molar equivalent of sodium-, potassium- or ammonium thiocyanate at a temperature range of 5° C to 30° C and, preferably, 15° C to 25° C for a period of time ranging from 2 to 4 hours to yield diethoxyphosphinyl isothiocyanate of formula (III). The reaction is slightly exothermic, but is easily controlled by a cooling bath.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04065466 |
| 出典データセット | uspto-grants-1977_12 |
| ORD ID | ord-5f2ee5d1d1af4eb5b68439b8c89fe2bb |
| 出典メモ | uspto-grants-1977_12 |