化工社化工社 化学情報印刷レポート · 研究参考用
Water → 1-(2,4-Dimethoxyphenyl)ethanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Acetovanillone | HCID 2214 | — |
| 反応物 | Dimethyl Sulfate | HCID 6497 | — |
| 反応物 | Sodium Carbonate | HCID 10340 | — |
| 溶媒 | Benzene | HCID 241 | — |
| 生成物 | 1-(2,4-Dimethoxyphenyl)ethanone | HCID 70016 | — |
反応手順
10 g of acetovanillone (0.06 mol) was methylated with 10.25 g of dimethyl sulfate (0.083 mol) and 8.0 g of sodium carbonate. The reaction mixture was stirred at 80°-90° C for 2 hr. while 6 ml of water were added dropwise over the last 1.2 hr. Addition of water, acidification, and extraction with benzene produced a nearly quantitative yield of 2,4-dimethoxyacetophenone containing less than 0.3% acetovanillone.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04065504 |
| 出典データセット | uspto-grants-1977_12 |
| ORD ID | ord-53ad9b6fae294a6cbcb7f7bd0053547c |
| 出典メモ | uspto-grants-1977_12 |