化工社化工社 化学情報印刷レポート · 研究参考用
2-(Methylamino)ethanol → 2-{2-[N-(2-Hydroxyethyl)methylamino]-5-thiadiazolyl}-1-methyl-5-nitroimidazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(Methylamino)ethanol | HCID 8016 | — |
| 反応物 | Piperidine | HCID 8082 | — |
| 反応物 | 2-(2-Piperidino-5-thiadiazolyl)-1-methyl-5-nitroimidazole | HCID 21390837 | — |
| 生成物 | 2-{2-[N-(2-Hydroxyethyl)methylamino]-5-thiadiazolyl}-1-methyl-5-nitroimidazole | HCID 68118756 | — |
反応手順
The preparation of the above compound is carried out essentially as described for the 2-piperidino derivative (Example 28), an equivalent of N-methylethanolamine replacing the piperidine. The pure compound melts at 158°-160° C. after recrystallization from methanol.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04065567 |
| 出典データセット | uspto-grants-1977_12 |
| ORD ID | ord-da559262e11a4cd4991ae08c78971761 |
| 出典メモ | uspto-grants-1977_12 |