化工社化工社 化学情報印刷レポート · 研究参考用
Piperidine → 2-[2-(4-Methyl-1-piperazinyl)-5-thiadiazolyl)-1-methyl-5-nitroimidazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Piperidine | HCID 8082 | — |
| 反応物 | 1-Methylpiperazine | HCID 53167 | — |
| 反応物 | 2-(2-Piperidino-5-thiadiazolyl)-1-methyl-5-nitroimidazole | HCID 21390837 | — |
| 生成物 | 2-[2-(4-Methyl-1-piperazinyl)-5-thiadiazolyl)-1-methyl-5-nitroimidazole | HCID 21390838 | — |
反応手順
The preparation of the above compound is carried out in the manner described for the 2-piperidino derivative (Example 28), an equivalent of 1-methylpiperazine replacing the piperidine. The crude product is purified by recrystallization from 2-methoxyethanol and melts at 242°-244° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04065567 |
| 出典データセット | uspto-grants-1977_12 |
| ORD ID | ord-174ca826ea4c410fb8561635a96caa59 |
| 出典メモ | uspto-grants-1977_12 |