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HRID 462239作成日:2026年10月25日

Tert-Butylamine → 2-(2-t-Butylamino-5-thiadiazolyl)-1-methyl-5-nitroimidazole

https://huagongshe.com/reaction/462239

反応式

関与物質

役割名称HCID仕込み量
反応物Tert-ButylamineHCID 6385—
反応物CyclohexylamineHCID 7965—
反応物2-(2-Cyclohexylamino-5-thiadiazolyl)-1-methyl-5nitroimidazoleHCID 21390861—
生成物2-(2-t-Butylamino-5-thiadiazolyl)-1-methyl-5-nitroimidazoleHCID 21390806—

反応手順

The preparation of the above compound is accomplished essentially by the procedure described for the 2-cyclohexylamino derivative (Example 38), an equivalent of t-butylamine replacing the cyclohexylamine. Recrystallization of the crude product from a mixture of ethyl acetate and acetone gives the pure compound melting at 249°-251° C.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US04065567
出典データセットuspto-grants-1977_12
ORD IDord-73ab2a9a9569489d90ea3ede1479815f
出典メモuspto-grants-1977_12