Triethylamine → HCID 20397918、化合物

HRID 462391ノート

反応式

HRID 462391 の反応式
[CH2:1]([SH:12])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].Br[CH2:14][CH:15]=[C:16]=[CH:17][CH2:18][CH2:19][C:20]([O:22][CH3:23])=[O:21].C(N(CC)CC)C>C(OCC)C>[C:20]([O:22][CH3:23])(=[O:21])[CH2:19][CH2:18][CH:17]=[C:16]=[CH:15][CH2:14][S:12][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11]

参加物

5

反応物 3

HCID 8471TriethylamineHCID 625701-UndecanethiolHCID 13470498HCID 13470498、化合物

生成物 1

HCID 20397918HCID 20397918、化合物収率 32.2%

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

A mixture of 376 mg of undecylmercaptan, 438 mg of methyl 7-bromohepta-4,5-dienoate and 0.278 ml of triethyl amine in 2 ml of diethyl ether were stirred at room temperature for 1 hour. The solvent was removed in vacuo and the residue chromatographed on silica gel eluting with hexane and toluene to give 210 mg of methyl 8-thianonadeca-4,5-dienoate having the following NMR spectrum which was run in deutochloroform solution with TMS as the internal standard.

後処理

  1. customThe solvent was removed in vacuo
  2. customthe residue chromatographed on silica gel eluting with hexane and toluene

出典と根拠

ORDレコード
ord-329c38f8063747abaf98633411b1332e
出典データセット
uspto-grants-1985_05
特許番号
US04515727

反応ノート

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