反応式
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[C:4]([NH:11][C:12]2[CH:17]=[CH:16][C:15]([OH:18])=[CH:14][CH:13]=2)[CH:3]=1.Cl.Cl[C:21]1C=CC(C(O)=O)=C(NC2C=CC(OC)=CC=2)C=1.S(OC)(OC)(=O)=O.ClC1C=CC(C(OC)=O)=C(NC2C=CC(OC)=CC=2)C=1.B(Br)(Br)Br>CO>[CH3:21][C:3]1[C:4]([NH:11][C:12]2[CH:17]=[CH:16][C:15]([OH:18])=[CH:14][CH:13]=2)=[C:5]([CH:9]=[CH:10][C:2]=1[Cl:1])[C:6]([OH:8])=[O:7]参加物
8
反応物 6
生成物 1
試薬・触媒・溶媒 1
実験手順
[I; R=4-Cl, R' and R"=H, Alk=CH3, OH at 4-position] is obtainable by esterification of 4-chloro-2-(4-hydroxyphenylamino)benzoic acid with methanol and hydrochloric acid; or by esterification of 4-chloro-2-(4-methoxyphenylamino)benzoic acid with dimethyl sulfate, followed by de-etherification of the resulting methyl 4-chloro-2-(4-methoxyphenylamino)benzoate with boron tribromide.
出典と根拠
- ORDレコード
- ord-a077546466954d6184495be609ecff98
- 出典データセット
- uspto-grants-1985_05
- 特許番号
- US04515980
関連ノート
読み込み中…