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Dibromoacetic Acid → 5-Methyl-6-nicotinoyl-1,3-benzodioxole-2-carboxylic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dibromoacetic Acid | HCID 12433 | — |
| 反応物 | (3,4-Dihydroxy-6-methylphenyl)-(3-pyridyl)-methanone | HCID 20396981 | — |
| 溶媒 | (Methanesulfinyl)methane--water (1/1) | HCID 23503278 | — |
| 生成物 | 5-Methyl-6-nicotinoyl-1,3-benzodioxole-2-carboxylic acid | HCID 22155990 | — |
反応手順
By reaction of 17.3 g (0.075 mol) of (3,4-dihydroxy-6-methylphenyl)-(3-pyridyl)-methanone with 16.5 g (0.075 mol) of dibromoacetic acid, analogously to Example 3, there is obtained 5-methyl-6-nicotinoyl-1,3-benzodioxole-2-carboxylic acid as sand-coloured crystals, m.p. 250°-232° C. (from dimethyl sulfoxide/water).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04517184 |
| 出典データセット | uspto-grants-1985_05 |
| ORD ID | ord-fb12de9e08f84669b438d02503898394 |
| 出典メモ | uspto-grants-1985_05 |