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1,2-Ethanedione, 1,2-bis(4-chlorophenyl)- → 4,5-Bis-(4-chlorophenyl)-5-hydroxy-2-thioxo-3-pyrroline-3-carbonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,2-Ethanedione, 1,2-bis(4-chlorophenyl)- | HCID 18946 | — |
| 反応物 | 2-Cyanoethanethioamide | HCID 1416277 | — |
| 触媒 | Piperidine | HCID 8082 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | 4,5-Bis-(4-chlorophenyl)-5-hydroxy-2-thioxo-3-pyrroline-3-carbonitrile | HCID 13236225 | — |
反応手順
A suspension of 22.3 g. 4,4'-dichlorobenzil, 6.5 g. 2-cyanothioacetamide, 20 drops of piperidine and 200 ml. chloroform is stirred for 20 hours at ambient temperature. The yellow precipitate obtained is filtered off with suction, well washed with chloroform and dried. There are obtained 22.0 g. of the desired compound in the form of yellow crystals; m.p. 213° C. (decomp.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04517185 |
| 出典データセット | uspto-grants-1985_05 |
| ORD ID | ord-8d02aad0da4c4edcb6cbbdcdbe59e98d |
| 出典メモ | uspto-grants-1985_05 |