Methane → 5-acetyl-6-methyl-2(1H)-pyridinone
反応式
[C:1]([C:4]1[CH:12]=[C:8](C(O)=O)[C:7](=[O:13])[NH:6][C:5]=1[CH3:14])(=[O:3])[CH3:2].C>C(O)(C)C>[C:1]([C:4]1[CH:12]=[CH:8][C:7](=[O:13])[NH:6][C:5]=1[CH3:14])(=[O:3])[CH3:2]参加物
4
実験手順
C-1. 5-Acetyl-6-methyl-2(1H)-pyridinone--A 10 g portion of 5-acetyl-1,2-dihydro-6-methyl-2-oxonicotinic acid was heated neat in a bath of a boiling mixture of diphenyl and diphenyl ether for 40 minutes and the mixture allowed to cool to room temperature. The reaction mixture was dissolved in hot isopropyl alcohol, treated with decolorizing charcoal and filtered, and the filtrate allowed to stand at room temperature for several hours. The separated product was collected and dried at 90°-95° C. to yield 4.3 g of 5-acetyl-6-methyl-2-(1H)-pyridinone, m.p. 193°-195° C.
後処理
- filtrationfiltered
- waitto stand at room temperature for several hours
- customThe separated product was collected
- customdried at 90°-95° C.
出典と根拠
- ORDレコード
- ord-2ebe0c1659494fc595566aa11daa9fee
- 出典データセット
- uspto-grants-1985_05
- 特許番号
- US04517190
反応ノート
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