Dimethyl Sulfate → Ethyl 2-methoxyimino-3,3-ethylenedioxy-4-chlorobutyrate
反応式
[OH:1][N:2]=[C:3]([C:9]1([O:15][CH2:14][CH2:13][O:12]1)[CH2:10][Cl:11])[C:4]([O:6][CH2:7][CH3:8])=[O:5].[C:16](=O)([O-])[O-].[K+].[K+].S(OC)(OC)(=O)=O>CC(C)=O>[CH3:16][O:1][N:2]=[C:3]([C:9]1([O:12][CH2:13][CH2:14][O:15]1)[CH2:10][Cl:11])[C:4]([O:6][CH2:7][CH3:8])=[O:5]参加物
5
実験手順
To a solution of ethyl 2-hydroxyimino-3,3-ethylenedioxy-4-chlorobutyrate (syn isomer, 0.5 g) in dried acetone (5 ml) was added potassium carbonate (0.29 g), and then dimethyl sulfate (0.265 g) was added dropwise thereto at ambient temperature with stirring. The mixture was stirred for 7 hours at ambient temperature and then filtered. The filtrate was evaporated to give ethyl 2-methoxyimino-3,3-ethylenedioxy-4-chlorobutyrate (syn isomer).
後処理
- stirringThe mixture was stirred for 7 hours at ambient temperature
- filtrationfiltered
- customThe filtrate was evaporated
出典と根拠
- ORDレコード
- ord-9d05b9435aa442ce844054a7cee97580
- 出典データセット
- uspto-grants-1985_05
- 特許番号
- US04518774
反応ノート
読み込み中…