化工社化工社 化学情報印刷レポート · 研究参考用
Sulfur Dioxide → 1-Bromo-4-(2-methylpropyl)benzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sulfur Dioxide | HCID 1119 | — |
| 反応物 | Isobutylbenzene | HCID 10870 | — |
| 反応物 | N-bromobutanimide | HCID 67184 | — |
| 生成物 | 1-Bromo-4-(2-methylpropyl)benzene | HCID 3789018 | 2% |
反応手順
To a mixture of 1.78 g (10 milliMoles) of N-bromosuccinimide in 20 ml of liquid sulfur dioxide at -30° C. is added 1.57 ml (10.0 mMoles) of isobutylbenzene. The mixture is stirred at -30° to -18° for 65 minutes, then worked up as above. Assay gives only 2% p-bromoisobutylbenzene and 88% recovered starting isobutylbenzene, indicating that the reaction with NBS is very slow at this temperature.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04518799 |
| 出典データセット | uspto-grants-1985_05 |
| ORD ID | ord-a31b5e83841e4b7c98d0fbe31b1aaed1 |
| 出典メモ | uspto-grants-1985_05 |