化工社化工社 化学情報印刷レポート · 研究参考用
Potassium Hydroxide → 1-Chloro-4-(3-phenylpropyl)benzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 反応物 | 4'-Chloro-3-phenylpropiophenone | HCID 247344 | — |
| 溶媒 | Diethylene Glycol | HCID 8117 | — |
| 生成物 | 1-Chloro-4-(3-phenylpropyl)benzene | HCID 13300857 | — |
反応手順
p-chlorophenyl phenylethyl ketone (25 g) was refluxed with hydrazine hydrate (13 g) and potassium hydroxide (18 g) in Digol (diethylene glycol) for one hour. The mixture was then distilled until the solution temperature in the still reached 175°. The mixture was then refluxed for 3 hours, cooled, poured into water and extracted with petroleum ether (Bpt 40°-60°). Evaporation of the extracts gave 1-(4-chlorophenyl)-3-phenylpropane Bbt. 110°/10-3 mm.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04520007 |
| 出典データセット | uspto-grants-1985_05 |
| ORD ID | ord-3ea19a854acc474080cbdd3124680918 |
| 出典メモ | uspto-grants-1985_05 |