関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Chloroacetonitrile | HCID 7856 | — |
| 反応物 | Sodium Carbonate | HCID 10340 | — |
| 反応物 | 1-Heptanamine, N-ethyl- | HCID 48038 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 2-[Ethyl(heptyl)amino]acetonitrile | HCID 20225324 | — |
反応手順
Combine 7.95 g (0.055 moles) ethyl(heptyl)amine, 3.5 ml (0.055 moles) chloroacetonitrile, 5.8 g (0.055 moles) sodium carbonate and 25 ml toluene in a sealed pressure tube. Heat to 125° C. for 18 hrs. Follow the progress of the reaction by thin layer chromatography on silica gel (CH3CN+MeOH+NH4OH, 85+10+5). At the completion of the reaction, filter the reaction mixture and evaporate the solvents to provide the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04544654 |
|---|
| 出典データセット | uspto-grants-1985_10 |
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| ORD ID | ord-848d384f4a9e4071b0ce402d368bbeaf |
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| 出典メモ | uspto-grants-1985_10 |
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