Acridine, 9-chloro-1-nitro- → HCID 178526555、化合物

HRID 463688ノート

反応式

HRID 463688 の反応式
Cl[C:2]1[C:3]2[C:8]([N:9]=[C:10]3[C:15]=1[C:14]([N+:16]([O-:18])=[O:17])=[CH:13][CH:12]=[CH:11]3)=[CH:7][CH:6]=[CH:5][CH:4]=2.Br.[NH:20]([C:22]1[S:23][CH2:24][CH2:25][N:26]=1)[NH2:21].C([O-])(=O)C.[Na+]>CO>[S:23]1[CH2:24][CH2:25][NH:26][C:22]1=[N:20][N:21]=[C:2]1[C:15]2[C:14]([N+:16]([O-:18])=[O:17])=[CH:13][CH:12]=[CH:11][C:10]=2[NH:9][C:8]2[C:3]1=[CH:4][CH:5]=[CH:6][CH:7]=2

参加物

5

反応物 3

HCID 146341Acridine, 9-chloro-1-nitro-HCID 517045Sodium AcetateHCID 27743032-Thiazolidinone, hydrazone, hydrobromide

生成物 1

HCID 178526555HCID 178526555、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

5.0 g of 9-chloro-1-nitroacridine, 3.8 g of 2-hydrazino-2-thiazoline hydrobromide and 3.17 g of anhydrous sodium acetate are dissolved in 250 ml of dry methanol, heated on a steam-bath for 1 hour and then left to stand overnight. The precipitated material is filtered and recrystallized from methanol. There is obtained 1-nitro-9-acridanone (2-thiazolidinylidene)hydrazone which beings to decompose from 152°.

後処理

  1. temperatureheated on a steam-bath for 1 hour
  2. waitleft
  3. filtrationThe precipitated material is filtered
  4. customrecrystallized from methanol

出典と根拠

ORDレコード
ord-638698b68fe248bb9dc519d196d72156
出典データセット
uspto-grants-1985_10
特許番号
US04544659

反応ノート

読み込み中…