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2,4,5-Trifluorobenzenesulfonyl chloride → tert-Butyl 1,3-thiazol-4-yl[(2,4,5-trifluorophenyl)sulfonyl]carbamate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,4,5-Trifluorobenzenesulfonyl chloride | HCID 2776979 | — |
| 反応物 | tert-butyl N-(1,3-thiazol-4-yl)carbamate | HCID 53241636 | — |
| 生成物 | tert-Butyl 1,3-thiazol-4-yl[(2,4,5-trifluorophenyl)sulfonyl]carbamate | HCID 59436528 | — |
反応手順
The above titled compound was prepared from 2,4,5-trifluorobenzenesulfonyl chloride (5.0 g, 0.022 mol) and thiazole-4-yl-carbamic acid tert-butyl ester (Preparation 72, 4.3 g, 0.022 mol) using the method of Preparation 453 to afford the product as a white solid (6.84 g, 80%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08541588B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-9761d7d53afa453cb43ddbba5f9cc9ec |
| 出典メモ | uspto-grants-2013_09 |