化工社化工社 化学情報印刷レポート · 研究参考用
Thionyl Chloride → 5-Methyl-3-phenylisoxazole-4-carbonyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 5-Methyl-3-phenyl-4-isoxazoloyl carboxylic acid | HCID 20265152 | — |
| 触媒 | Pyridine | HCID 1049 | — |
| 生成物 | 5-Methyl-3-phenylisoxazole-4-carbonyl chloride | HCID 85624 | — |
反応手順
A mixture of 111.76 g of 5-methyl-3-phenyl-4-isoxazoloyl carboxylic acid, 6 drops of pyridine and 29.5 ml of thionyl chloride is stirred under reflux for 4 hrs. The excess thionyl chloride is evaporated in vacuo. Distillation of the residue yields 113.74 g of yellow liquid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04544670 |
| 出典データセット | uspto-grants-1985_10 |
| ORD ID | ord-e5e56676ef5d48e9b65a67a4cd85f5d8 |
| 出典メモ | uspto-grants-1985_10 |