2-Amino-4-methoxy-6-methyl-1,3,5-triazine → Metsulfuron-methyl

HRID 463983

反応式

HRID 463983 の反応式
[NH2:1][C:2]1[N:7]=[C:6]([O:8][CH3:9])[N:5]=[C:4]([CH3:10])[N:3]=1.[CH3:11][O:12][C:13]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[S:21]([N:24]=[C:25]=[O:26])(=[O:23])=[O:22])=[O:14]>C(Cl)Cl>[CH3:9][O:8][C:6]1[N:5]=[C:4]([CH3:10])[N:3]=[C:2]([NH:1][C:25]([NH:24][S:21]([C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=2[C:13]([O:12][CH3:11])=[O:14])(=[O:23])=[O:22])=[O:26])[N:7]=1

参加物

4

反応物 2

HCID 154662-Amino-4-methoxy-6-methyl-1,3,5-triazineHCID 156281Benzoic acid, 2-(isocyanatosulfonyl)-, methyl ester

生成物 1

HCID 52999Metsulfuron-methyl

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

To an anhydrous suspension of 1.4 g of 2-amino-4-methoxy-6-methyl-1,3,5-triazine in 25 ml of methylene chloride was added with stirring at ambient temperatures and pressure 2.4 g of 2-methoxycarbonylbenzenesulfonylisocyanate. The mixture was thereafter stirred for 16 hours and filtered. The filtrate was evaporated to dryness, the residue was triturated with butyl chloride and the product removed by filtration. The product thus obtained melted at 165°, and had absorption peaks in the infrared at 1550, 1600, 1680 and 1700 cm-1 and in the NMR spectrum at 2.5, 3.65, 4.0 with an aromatic multiplet at 7.2-8 ppm.

後処理

  1. additionwas added
  2. filtrationfiltered
  3. customThe filtrate was evaporated to dryness
  4. customthe residue was triturated with butyl chloride
  5. customthe product removed by filtration
  6. customabsorption peaks in the

出典と根拠

ORDレコード
ord-8d86eb4cd7744770a209c1bea015d4e3
出典データセット
uspto-grants-1985_10
特許番号
US04545808

関連ノート

読み込み中…