4-(4-Chlorophenyl)but-2-yn-1-ol → HCID 13660260、化合物

HRID 464029ノート

反応式

HRID 464029 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]#[C:10][CH2:11][OH:12])=[CH:4][CH:3]=1.[H][H]>CC(C)=O.[Pd].CC([O-])=O.CC([O-])=O.[Pb+2]>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8]/[CH:9]=[CH:10]\[CH2:11][OH:12])=[CH:6][CH:7]=1

参加物

5

反応物 2

HCID 136602584-(4-Chlorophenyl)but-2-yn-1-olHCID 178418361HCID 178418361、化合物

生成物 1

HCID 13660260HCID 13660260、化合物

試薬・触媒・溶媒 2

HCID 131709914Lindlars catalyst触媒HCID 180Acetone溶媒

実験手順

Dissolve 10 g (0.055 mole) of 4-(4-chlorophenyl)but-2-yn-1-ol in 100 ml of acetone. Add 0.6 g of Lindlar's catalyst. Stir the mixture under 1 atmosphere of hydrogen at room temperature. Follow the progress of the reaction by NMR. At the completion of the reaction, filter to remove the catalyst and evaporate to yield the title compound.

後処理

  1. customthe progress of the reaction by NMR
  2. customAt the completion of the reaction
  3. filtrationfilter
  4. customto remove the catalyst
  5. customevaporate

出典と根拠

ORDレコード
ord-e9db3053a42a47aca4797f058a311f27
出典データセット
uspto-grants-1985_10
特許番号
US04545995

反応ノート

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