N,N-Diethyl-1-heptanamine → 4(3-Chlorophenyl)-N,N-diethyl-N-heptyl-2-buten-1-aminium chloride

HRID 464033ノート

反応式

HRID 464033 の反応式
[Cl:1]C1C=CC=C(CC=CCCl)C=1.Cl[CH:14]([CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[CH:19]=1)[CH:15]=[CH2:16].[CH2:25]([N:27]([CH2:35][CH3:36])[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])[CH3:26]>O>[Cl-:1].[Cl:24][C:20]1[CH:19]=[C:18]([CH2:17][CH:14]=[CH:15][CH2:16][N+:27]([CH2:25][CH3:26])([CH2:35][CH3:36])[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])[CH:23]=[CH:22][CH:21]=1

参加物

5

反応物 3

HCID 12496130N,N-Diethyl-1-heptanamineHCID 202636013-Chloro-4-(3-chlorophenyl)-1-buteneHCID 538104491-Chloro-3-(4-chloro-2-butenyl)benzene

生成物 1

HCID 704471924(3-Chlorophenyl)-N,N-diethyl-N-heptyl-2-buten-1-aminium chloride

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

Heat a mixture of 6.0 g (0.03 mole) of 1-chloro-3-(4-chloro-2-butenyl)benzene and 3-chloro-4-(3-chlorophenyl)-1-butene (in a ratio of 4:3) and 5.1 g (0.03 mole) N,N-diethylheptanamine at 100° C. for about 20 hours. Dissolve in 100 ml water and wash with 3×75 ml hexane and then extract with methylene chloride. Dry methylene chloride extract over magnesium sulfate, filter and evaporate the solvent in vacuo to provide the title compound.

後処理

  1. temperatureHeat
  2. washwash with 3×75 ml hexane
  3. extractionextract with methylene chloride
  4. extractionDry methylene chloride extract over magnesium sulfate
  5. filtrationfilter
  6. customevaporate the solvent in vacuo

出典と根拠

ORDレコード
ord-71f1b03136004ccd85e37aba9d16dd88
出典データセット
uspto-grants-1985_10
特許番号
US04545995

反応ノート

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