Ethyl orthoformate → 4-Chloro[1,2,4]triazolo[4,3-a]quinoxaline
反応式
[Cl:1][C:2]1[C:11]([NH:12][NH2:13])=[N:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.[CH:14](OCC)(OCC)OCC>>[Cl:1][C:2]1[C:11]2[N:10]([CH:14]=[N:13][N:12]=2)[C:9]2[C:4]([N:3]=1)=[CH:5][CH:6]=[CH:7][CH:8]=2参加物
3
実験手順
2-Chloro-3-hydrazinoquinoxaline (9.0 g., 0.046 mole) the product of Example 1, was stirred with triethyl orthoformate (90 ml.) at 100° C. for one hour. The mixture was cooled to room temperature and the solid precipitate was collected by filtration and washed with cyclohexane and dried to afford 8.8 g. (94% yield) of 4-chloro-[1,2,4]triazolo[4,3-a]quinoxaline, m.p. 287°-290° C. (decomp.). Mass spectrum: m/e, 204 (P).
後処理
- filtrationthe solid precipitate was collected by filtration
- washwashed with cyclohexane
- customdried
- customto afford 8.8 g
出典と根拠
- ORDレコード
- ord-70b80ffed64d497681be598e3df21903
- 出典データセット
- uspto-grants-1985_10
- 特許番号
- US04547501
反応ノート
読み込み中…