Methanol → Methyl 3-(4-methylphenyl)-2-propenoate

HRID 464717

反応式

HRID 464717 の反応式
[CH3:1][C:2]1[CH:12]=[CH:11][C:5]([CH:6]=[CH:7][C:8]([OH:10])=[O:9])=[CH:4][CH:3]=1.S(=O)(=O)(O)O.[CH3:18]O>>[CH3:18][O:9][C:8](=[O:10])[CH:7]=[CH:6][C:5]1[CH:11]=[CH:12][C:2]([CH3:1])=[CH:3][CH:4]=1

参加物

4

反応物 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 158353-(p-Tolyl)acrylic acid

生成物 1

HCID 589472Methyl 3-(4-methylphenyl)-2-propenoate

実験手順

A suspension of 300 g of p-methylcinnamic acid (J. Chem. Soc., Chem. Comm., 471, 1976) and 25 ml of concentrated sulfuric acid in 1.7 liters of methanol is heated to reflux for 24 hours. The solution is concentrated, cooled and filtered to give as a white solid, p-methylcinnamic acid methyl ester, mp 55°-56° C.

後処理

  1. temperatureis heated
  2. temperatureto reflux for 24 hours
  3. concentrationThe solution is concentrated
  4. temperaturecooled
  5. filtrationfiltered

出典と根拠

ORDレコード
ord-f1736f1382ed4ff6ba975d778496976c
出典データセット
uspto-grants-1985_10
特許番号
US04548947

関連ノート

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