Nitromethane → HCID 54082890、化合物

HRID 464718

反応式

HRID 464718 の反応式
[CH3:1][C:2]1[CH:13]=[CH:12][C:5]([CH:6]=[CH:7][C:8]([O:10][CH3:11])=[O:9])=[CH:4][CH:3]=1.[N+:14]([CH3:17])([O-:16])=[O:15].CN(C)C(=N)N(C)C>C(OCC)C.Cl>[CH3:11][O:10][C:8](=[O:9])[CH2:7][CH:6]([C:5]1[CH:12]=[CH:13][C:2]([CH3:1])=[CH:3][CH:4]=1)[CH2:17][N+:14]([O-:16])=[O:15]

参加物

6

反応物 3

HCID 6375NitromethaneHCID 664601,1,3,3-TetramethylguanidineHCID 589472Methyl 3-(4-methylphenyl)-2-propenoate

生成物 1

HCID 54082890HCID 54082890、化合物

試薬・触媒・溶媒 2

HCID 313Hydrochloric Acid溶媒HCID 3283Diethyl Ether溶媒

実験手順

A mixture to 300 g of p-methylcinnamic acid, methyl ester, 500 g of nitromethane and 39 g of tetramethylguanidine is allowed to stir at room temperature for 72 hours. The solution is diluted with diethyl ether and (1 liter, 1 N) aqueous hydrochloric acid solution added. The organic layer is separated, dried over anhydrous magnesium sulfate, and evaporated to give 4-nitro-3-(4-methylphenyl) butanoic acid methyl ester.

後処理

  1. additionadded
  2. customThe organic layer is separated
  3. dry with materialdried over anhydrous magnesium sulfate
  4. customevaporated

出典と根拠

ORDレコード
ord-8224e872398d4797b5f96db9535e17b7
出典データセット
uspto-grants-1985_10
特許番号
US04548947

関連ノート

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