Nitromethane → HCID 54303925、化合物

HRID 464737

反応式

HRID 464737 の反応式
[CH3:1][O:2][C:3](=[O:14])[CH:4]=[CH:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[CH:8][CH:7]=1.[N+:15]([CH3:18])([O-:17])=[O:16].CN(C)C(=N)N(C)C>C(OCC)C.Cl>[CH3:1][O:2][C:3](=[O:14])[CH2:4][CH:5]([C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[CH:8][CH:7]=1)[CH2:18][N+:15]([O-:17])=[O:16]

参加物

6

反応物 3

HCID 6375NitromethaneHCID 664601,1,3,3-TetramethylguanidineHCID 928414-Methoxycinnamate methyl ester

生成物 1

HCID 54303925HCID 54303925、化合物

試薬・触媒・溶媒 2

HCID 313Hydrochloric Acid溶媒HCID 3283Diethyl Ether溶媒

実験手順

A mixture of 288 g of 4-methoxycinnamic acid methyl ester, 500 g of nitromethane and 23 g of tetramethylguanidine is allowed to stir for 72 hours. The solution is diluted with diethyl ether and aqueous hydrochloric acid solution (1 N, 1 liter) is added. The organic layer is separated, dried over anhydrous magnesium sulfate, and evaporated to give 4-nitro-3-(4-methoxyphenyl)butanoic acid methyl ester.

後処理

  1. additionis added
  2. customThe organic layer is separated
  3. dry with materialdried over anhydrous magnesium sulfate
  4. customevaporated

出典と根拠

ORDレコード
ord-18f9293897da46bea096e0dcb16c6f79
出典データセット
uspto-grants-1985_10
特許番号
US04548947

関連ノート

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