2,4-Dichlorobenzoic Acid → 4-Chloro-2-((4-methoxyphenyl)amino)benzoic acid

反応式

Cl[C:2]1[CH:10]=[C:9]([Cl:11])[CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[CH3:12][O:13][C:14]1[CH:20]=[CH:19][C:17]([NH2:18])=[CH:16][CH:15]=1>>[Cl:11][C:9]1[CH:8]=[CH:7][C:3]([C:4]([OH:6])=[O:5])=[C:2]([NH:18][C:17]2[CH:19]=[CH:20][C:14]([O:13][CH3:12])=[CH:15][CH:16]=2)[CH:10]=1

参加物

反応物 2

HCID 57872,4-Dichlorobenzoic Acid

HCID 7732P-Anisidine

生成物 1

HCID 666744-Chloro-2-((4-methoxyphenyl)amino)benzoic acid収率 60%

実験手順

4-Chloro-2-(4-methoxyphenylamino)benzoic acid [VII; R=4-Cl, R"=H, OR°=4-OCH3 ] was prepared from 2,4-dichlorobenzoic acid and 4-methoxyaniline according to the procedure of Example 1, part (a), and was obtained in about 60% yield as a green-grey solid.

後処理

customwas obtained in about 60% yield as a green-grey solid

出典と根拠

ORDレコード: ord-68a947766ea045a1944dd764daab91f1
出典データセット: uspto-grants-1985_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04549016

反応ノート

読み込み中…

参加物