2-(3-Hydroxy-1,2,3,4-tetrahydronaphthalenyl)-1-methylpiperidine → 2-(1,2,3,4,5,8-Hexahydro-3-hydroxynaphthalenyl)-1-methylpiperidine

HRID 46505ノート

反応式

HRID 46505 の反応式
[OH:1][CH:2]1[CH2:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]([CH:12]2[CH2:17][CH2:16][CH2:15][CH2:14][N:13]2[CH3:18])[CH2:3]1.OC1C(O)C2C(=CC=CC=2)CC1C1CCN(C)C1>>[OH:1][CH:2]1[CH2:11][C:10]2[CH2:9][CH:8]=[CH:7][CH2:6][C:5]=2[CH:4]([CH:12]2[CH2:17][CH2:16][CH2:15][CH2:14][N:13]2[CH3:18])[CH2:3]1

参加物

3

反応物 2

HCID 203873702-(3-Hydroxy-1,2,3,4-tetrahydronaphthalenyl)-1-methylpiperidineHCID 203873713-(3,4-Dihydroxy-1,2,3,4-tetrahydro-2-naphthalenyl)-1-methylpyrrolidine

生成物 1

HCID 203873782-(1,2,3,4,5,8-Hexahydro-3-hydroxynaphthalenyl)-1-methylpiperidine

実験手順

Following the procedure of Example 6, part D, but substituting the 2-(3-hydroxy-1,2,3,4-tetrahydronaphthalenyl)-1-methylpiperidine for the 3-(3,4-dihydroxy-1,2,3,4-tetrahydro-2-naphthalenyl)-1-methyl pyrrolidine, the title C compound is obtained.

後処理

  1. customthe title C compound is obtained

出典と根拠

ORDレコード
ord-874eb9e7752e4626899fe12bbf7795fa
出典データセット
uspto-grants-1979_11
特許番号
US04173640

反応ノート

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