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Acetone → 2,3,5,6-Tetrahydro-6-phenyl-7-methoxycarbonylmethylimidazo-[2,1-b]-thiazolium bromide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetone | HCID 180 | — |
| 反応物 | (+-)-Tetramisole | HCID 3913 | — |
| 反応物 | Bromoacetic Acid | HCID 6227 | — |
| 生成物 | 2,3,5,6-Tetrahydro-6-phenyl-7-methoxycarbonylmethylimidazo-[2,1-b]-thiazolium bromide | HCID 20261919 | 81% |
反応手順
2 g (0.01 mol) of 2,3,5,6-tetrahydro-6-phenylimidazo-[2,1-b]-thiazole are dissolved in 20 ml of acetone and added with 1.53 g (0.01 mol) of methyl ester of monobromacetic acid. After 12 hours the residue is filtered-off and washed with acetone to give 2.86 g (81%) of 2,3,5,6-tetrahydro-6-phenyl-7-methoxycarbonylmethylimidazo-[2,1-b]-thiazolium bromide melting at 81°-82° C. (from dioxane).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04550170 |
| 出典データセット | uspto-grants-1985_10 |
| ORD ID | ord-282bffce6faf4ef09327d9ede0c4e36e |
| 出典メモ | uspto-grants-1985_10 |