化工社化工社 化学情報印刷レポート · 研究参考用
tert-Butanol → N-boc-4-chlorobenzenesulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | tert-Butanol | HCID 6386 | — |
| 反応物 | 4-Chlorobenzenesulfonyl isocyanate | HCID 138587 | — |
| 生成物 | N-boc-4-chlorobenzenesulfonamide | HCID 14796817 | — |
反応手順
The commercially available p-chlorophenylsulfonyl isocyanate (15.0 g, 58.6 mmol) is added dropwise to t-butanol (90 ml) and the mixture is allowed to stir at room temperature for 60 hours. The solvent is evaporated and the white solid is recrystallized from hexane and ethylacetate to obtain N-t-butoxycarbonyl-p-chlorophenylsulfonamide, m.p. 98°-99° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05153214 |
| 出典データセット | uspto-grants-1992_10 |
| ORD ID | ord-c6fefe3fbe4c4b8ba246ce545c3a9649 |
| 出典メモ | uspto-grants-1992_10 |