Isothiocyanic acid, p-dimethylaminophenyl ester → N-[2,6-bis(1-Methylethyl)phenyl]-2-[[[[4-(dimethylamino)phenyl]amino]thioxomethyl](phenylmethyl)amino]acetamide

HRID 465658

反応式

HRID 465658 の反応式
[CH3:1][CH:2]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH:10]([CH3:12])[CH3:11])[C:5]=1[NH:13][C:14](=[O:31])[CH2:15][NH:16][CH2:17]C(C1C=CC=CC=1)C1C=CC=CC=1)[CH3:3].[CH3:32][N:33]([CH3:43])[C:34]1[CH:39]=[CH:38][C:37]([N:40]=[C:41]=[S:42])=[CH:36][CH:35]=1>>[CH3:3][CH:2]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH:10]([CH3:12])[CH3:11])[C:5]=1[NH:13][C:14](=[O:31])[CH2:15][N:16]([C:41]([NH:40][C:37]1[CH:38]=[CH:39][C:34]([N:33]([CH3:43])[CH3:32])=[CH:35][CH:36]=1)=[S:42])[CH2:17][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)[CH3:1]

参加物

3

反応物 2

HCID 75047Isothiocyanic acid, p-dimethylaminophenyl esterHCID 19874997N-[2,6-bis(1-Methylethyl)phenyl]-2-[(2,2-diphenylethyl)amino]acetamide

生成物 1

HCID 19874983N-[2,6-bis(1-Methylethyl)phenyl]-2-[[[[4-(dimethylamino)phenyl]amino]thioxomethyl](phenylmethyl)amino]acetamide

実験手順

When in the procedure of Example 80 an appropriate amount of the product of Example 71 was substituted for the product of Example 70 and an appropriate amount of 4-dimethylaminophenylisothiocyanate was substituted for ethyl isocyanato acetate the title compound was obtained. Total yield, 0.84 g (80%).

出典と根拠

ORDレコード
ord-85e7b112d9134592a890337d9c27b1c6
出典データセット
uspto-grants-1992_10
特許番号
US05153226

関連ノート

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