化工社化工社 化学情報印刷レポート · 研究参考用
Methyl 2-chloroacrylate → 5-Chloro-5-methoxycarbonyl-3-thiapentanamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl 2-chloroacrylate | HCID 6659 | — |
| 反応物 | 2-Mercaptoacetamide | HCID 12961 | — |
| 反応物 | 1,4-Dioxane | HCID 31275 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 5-Chloro-5-methoxycarbonyl-3-thiapentanamide | HCID 19875485 | — |
反応手順
2-Mercaptoacetamide (18.79 g) was stirred in a mixture of dry 1,4-dioxan (200 ml) and dry pyridine (33.5 ml)) whilst methyl 2-chloroacrylate (24.88 g) was added dropwise over 15 minutes. The mixture was stirred for 1 hour then stood overnight. The resultant mixture contained the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05153330 |
| 出典データセット | uspto-grants-1992_10 |
| ORD ID | ord-7ee7a85c10d545b4b1ed1df425ca1296 |
| 出典メモ | uspto-grants-1992_10 |