Hydrochloric Acid → 2-(Decylthio)ethanamine hydrochloride

HRID 466038

反応式

HRID 466038 の反応式
[CH2:1]([SH:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[CH2:12]([C:14]1OCC[N:18]=1)C.[ClH:19]>[Cl-].[Zn+2].[Cl-]>[ClH:19].[CH2:1]([S:11][CH2:12][CH2:14][NH2:18])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 89171-DecanethiolHCID 664122-Ethyl-2-oxazoline

生成物 1

HCID 1511622-(Decylthio)ethanamine hydrochloride

試薬・触媒・溶媒 1

HCID 3007855Zincchloride触媒

反応条件

温度
140 °C

実験手順

Approximately 225 pounds of decylmercaptan are loaded into a jacketed reactor equipped with an agitator. 1.25 pounds of zinc chloride catalyst are added through the manhole. The system is heated to approximately 140° C. and 130 pounds of 2-ethyl-2-oxazoline are added at the rate of 3 lbs/min in about 45 minutes. About 30 minutes are allowed for the reaction to be completed, the reactor cooled to approximately 120° C. and 155 pounds of 32 weight percent hydrochloric acid are then added to the reaction mixture. The reactor is heated to 150°-160° C., at which time the vapor pressure of the system is approximately 60 psi. The temperature is maintained near 150° C. for 2 hours to complete the hydrolysis.

後処理

  1. customequipped with an agitator
  2. customAbout 30 minutes are allowed for the reaction
  3. temperaturethe reactor cooled to approximately 120° C.
  4. temperatureThe reactor is heated to 150°-160° C., at which time the vapor pressure of the system
  5. temperatureThe temperature is maintained near 150° C. for 2 hours
  6. customthe hydrolysis

出典と根拠

ORDレコード
ord-e9947fbbbf9443869cceb64edc940dce
出典データセット
uspto-grants-1992_10
特許番号
US05155131

関連ノート

読み込み中…