Benzoyl chloride → HCID 14049623、化合物

HRID 466134ノート

反応式

HRID 466134 の反応式
C[Si](C)(C)[O:3][C:4]1[CH:9]=[C:8]([O:10][Si](C)(C)C)[CH:7]=[CH:6][N:5]=1.[C:17](Cl)(=[O:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>ClCCl>[C:17]([O:3][C:4]1[CH:9]=[C:8]([O:10][C:17](=[O:24])[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:7]=[CH:6][N:5]=1)(=[O:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

参加物

4

反応物 2

HCID 7412Benzoyl chlorideHCID 21819823HCID 21819823、化合物

生成物 1

HCID 14049623HCID 14049623、化合物収率 24.6%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

To 4.0 g of 2,4-bis(trimethylsilyloxy)-pyridine in 50 ml of dichloromethane were added 2.65 g of benzoyl chloride and 0.2 ml of stannic chloride, and the mixture was stirred at room temperature for one hour. The solvent was distilled off and the residue was subjected to silica gel chromatography using ethyl acetate-benzene (2:3) as an eluent to produce 0.74 g of the title compound in a yield of 14.8%.

後処理

  1. distillationThe solvent was distilled off

出典と根拠

ORDレコード
ord-19ced059d5cf4a31866ca35ad1ec7956
出典データセット
uspto-grants-1992_10
特許番号
US05155113

反応ノート

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