Benzoyl chloride → HCID 178510098、化合物

HRID 466160ノート

反応式

HRID 466160 の反応式
C(N(CC)CC)C.[C:8](Cl)(=[O:15])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.[C:17]([C:19]1[C:20]([OH:26])=[N:21][C:22]([OH:25])=[CH:23][CH:24]=1)#[N:18]>CN(C)C(=O)C>[C:8]([O:25][C:22]1[N:21]=[C:20]([OH:26])[C:19]([C:17]#[N:18])=[CH:24][CH:23]=1)(=[O:15])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

参加物

5

反応物 3

HCID 7412Benzoyl chloride2 回HCID 8471Triethylamine2 回HCID 178510101HCID 178510101、化合物

生成物 1

HCID 178510098HCID 178510098、化合物収率 60%

試薬・触媒・溶媒 1

HCID 31374Dimethylacetamide溶媒

実験手順

A 0.51 ml quantity of triethylamine and 0.43 ml of benzoyl chloride were added to a solution of 1.00 g of 3-cyano-2,6-dihydroxypyridine in 40 ml of N,N-dimethylacetamide. The mixture was stirred at room temperature for 15 minutes. To the reaction mixture were added 0.51 ml of triethylamine and 0.43 ml of benzoyl chloride, and the mixture was stirred at room temperature for 15 minutes. The reaction mixture was filtered and the filtrate was concentrated under a reduced pressure. The concentrate was washed with chloroform and with water, giving 1.06 g of the title compound in a yield of 60%.

後処理

  1. stirringthe mixture was stirred at room temperature for 15 minutes
  2. filtrationThe reaction mixture was filtered
  3. concentrationthe filtrate was concentrated under a reduced pressure
  4. washThe concentrate was washed with chloroform and with water

出典と根拠

ORDレコード
ord-4cdb991e889246a897f32b38fa11cba4
出典データセット
uspto-grants-1992_10
特許番号
US05155113

反応ノート

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