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Butyl bromide → 2,3-Dichloro-4-methoxy-N-n-butylaniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Butyl bromide | HCID 8002 | — |
| 反応物 | Sodium Bicarbonate | HCID 516892 | — |
| 反応物 | 2,3-Dichloro-4-methoxyaniline | HCID 13690639 | — |
| 溶媒 | 2-Methoxyethanol | HCID 8019 | — |
| 生成物 | 2,3-Dichloro-4-methoxy-N-n-butylaniline | HCID 13688451 | — |
反応手順
A mixture of 2,3-dichloro-4-methoxyaniline (19.2 g), n-butylbromide (22.0 g), sodium hydrogen carbonate (40 g) and methylcellosolve (350 ml) is stirred at 95°-100° C. for about 48 hours. The cooled mixture is filtered, and the filtrate is evaporated in vacuo. The remaining material is washed with water and is thereafter recrystallized from ethanol to give the title compound with a melting point of 47°-49° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05157039 |
| 出典データセット | uspto-grants-1992_10 |
| ORD ID | ord-8fb866fbda2a421cb6d9f91b2097482b |
| 出典メモ | uspto-grants-1992_10 |