反応式
[NH2:1][C:2]1[C:7]([NH2:8])=[C:6]([CH3:9])[CH:5]=[CH:4][N:3]=1.[C:10](O)(=O)[CH3:11]>>[CH3:10][C:11]1[NH:8][C:7]2[C:2]([N:1]=1)=[N:3][CH:4]=[CH:5][C:6]=2[CH3:9]参加物
3
実験手順
The title compound was prepared from 2,3-diamino-4-picoline (0.246 g, 2 mmol) and acetic acid (0.15 ml) according to the procedure described in Step 1 of Example 9. The crude product was purified by flash chromatography on silica-gel using EtOAc-MeOH (9:1) to give the pure product (0.25 g, 85%) as a light brown solid.
後処理
- customThe crude product was purified by flash chromatography on silica-gel
出典と根拠
- ORDレコード
- ord-26cedda587d24dfca7f9eca11b9d524b
- 出典データセット
- uspto-grants-1992_10
- 特許番号
- US05157026
関連ノート
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