関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Ammonium Hydroxide | HCID 14923 | — |
| 反応物 | Phosphorus oxychloride | HCID 24813 | — |
| 反応物 | HCID 178437532 | HCID 178437532 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | 5-chloro-2-ethyl-7-methyl-3H-Imidazo[4,5-b]pyridine | HCID 19385734 | — |
反応手順
A mixture of the N-oxide (29.75 g, 0.168 mol), CHCl3 (25 mL) and POCl3 (160 mL) was heated to 80° C. for 1 hours. After pouring over ice, the mixture was neutralized by careful addition of NH4OH and extracted with EtOAc. Concentration gave 23.8 g of 5-chloro-2-ethyl-7-methylimidazo[4,5-b]pyridine as a solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05157026 |
|---|
| 出典データセット | uspto-grants-1992_10 |
|---|
| ORD ID | ord-8064d2a62fa4477887173a559f968371 |
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| 出典メモ | uspto-grants-1992_10 |
|---|
