化工社化工社 化学情報印刷レポート · 研究参考用
(4-Amino-3-nitrophenyl)methanol → (3,4-Diaminophenyl)methanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (4-Amino-3-nitrophenyl)methanol | HCID 12902831 | — |
| 反応物 | HCID 178418361 | HCID 178418361 | — |
| 触媒 | Nickel | HCID 935 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | (3,4-Diaminophenyl)methanol | HCID 12902832 | 82% |
反応手順
Six grams (0.035 mole) of 4-amino-3-nitrobenzyl alcohol, 95 ml. of tetrahydrofuran and 0.5 g. of Raney Nickel were hydrogenated at 40 psi at room temperature until 3 moles of hydrogen were absorbed. The catalyst was filtered and the filtrate was evaporated in vacuo to yield 4.83 g. (82 percent yield) of 3,4-diaminobenzyl alcohol, mp. 74°-75° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04174454 |
| 出典データセット | uspto-grants-1979_11 |
| ORD ID | ord-38b1408d5185446da164fb486c4e7a6f |
| 出典メモ | uspto-grants-1979_11 |