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Sodium Acetate → 5-[(3,5-Di-2-propenyl-4-hydroxyphenyl)-methylene]-2-thioxo-4-thiazolidinone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Acetate | HCID 517045 | — |
| 反応物 | Rhodanine | HCID 1201546 | — |
| 反応物 | 3,5-Di-(2-propenyl)-4-hydroxybenzaldehyde | HCID 12047778 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 5-[(3,5-Di-2-propenyl-4-hydroxyphenyl)-methylene]-2-thioxo-4-thiazolidinone | HCID 54005288 | 94.6% |
反応手順
3,5-di-(2-propenyl)-4-hydroxybenzaldehyde (50.5 g), 36.6 g of rhodanine and 164 g of sodium acetate were heated together at reflux temperature in 1.25 liter of acetic acid for 14.5 hours. The resultant solution was cooled, poured into 2 1 of ice water to yield, upon separation, about 75 g of 5-[(3,5-di-2-propenyl-4-hydroxyphenyl)methylene]-2-thioxo-4-thiazolidinone, m.p. 157-160° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05158966 |
| 出典データセット | uspto-grants-1992_10 |
| ORD ID | ord-317abbfdf14b4a25b87820759bc34f03 |
| 出典メモ | uspto-grants-1992_10 |