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Propylene Oxide → N-Chlorophthalimide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Propylene Oxide | HCID 6378 | — |
| 反応物 | Phthalimide | HCID 6809 | — |
| 反応物 | Chlorine | HCID 24526 | — |
| 反応物 | Diisopropylethylamine | HCID 81531 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | N-Chlorophthalimide | HCID 18997 | — |
反応手順
To 150 ml. of dry methylene chloride were added 7.35 g. (0.05 mole) of phthalimide followed by 17.5 ml. (5 equiv.) of propylene oxide and 0.065 g. (0.5 mmoles) of diisopropylethylamine. The mixture was cooled to 0° C. and saturated with chlorine. The mixture was stirred for about 24 hours to provide approximately 50% conversion to N-chlorophthalimide.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04175082 |
| 出典データセット | uspto-grants-1979_11 |
| ORD ID | ord-30bcf861e6db4b1091088b181ae54e82 |
| 出典メモ | uspto-grants-1979_11 |