Water → Triphenylen-2-ol

HRID 467417ノート

反応式

HRID 467417 の反応式
C[O:2][C:3]1[CH:20]=[CH:19][C:18]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=1.B(Br)(Br)Br.[B].O>C(Cl)Cl>[OH:2][C:3]1[CH:20]=[CH:19][C:18]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=1

参加物

5

反応物 3

HCID 962WaterHCID 587694502-MethoxytriphenyleneHCID 86647723Boron boron tribromide

生成物 1

HCID 3016112Triphenylen-2-ol収率 95.1%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒2 回

反応条件

温度
-78 °C

実験手順

Under an argon atmosphere, 13.9 g of 2-methoxytriphenylene was placed in a flask, and 300 mL of methylene chloride was added. The reaction solution was cooled to −78° C., and 54 mL of a solution of 1M boron boron tribromide in methylene chloride was dropwise added thereto. The reaction solution was stirred for 5 hours while increasing temperature of the reaction solution to room temperature. 100 mL of water was added to the reaction solution, followed by filtration. The resulting solid was washed with water and methanol to obtain 12.5 g (yield: 95%) of 2-hydroxytriphenylene.

後処理

  1. temperaturewhile increasing temperature of the reaction solution to room temperature
  2. filtrationfollowed by filtration
  3. washThe resulting solid was washed with water and methanol

出典と根拠

ORDレコード
ord-0e905611116c471e947e53fab1e5cbb2
出典データセット
uspto-grants-2014_01
特許番号
US08623520B2

反応ノート

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