化工社化工社 化学情報印刷レポート · 研究参考用
Sodium Hydroxide → Dihydroandrostenedione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Epiandrosterone | HCID 441302 | — |
| 反応物 | Jones' reagent | HCID 131709961 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | Dihydroandrostenedione | HCID 222865 | 95.1% |
反応手順
To the mixture of 6 (5 g, 17.2 mmol) and 75 ml acetone at room temperature 1.5 ml of Jones reagent (CrO3, H2SO4, H2O) was added by drops. After the reaction was completed, NaOH was added, liquid phase was separated and then 90 ml water was added. The resulting precipitate was filtered off to afford product 7 (4.72 g, 94%). M.p. 134-137° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08623849B2 |
| 出典データセット | uspto-grants-2014_01 |
| ORD ID | ord-08e7bcdbab2549c384510081d8f10672 |
| 出典メモ | uspto-grants-2014_01 |