Hexyl isocyanate → 1-Butyl-3-hexyl-1-(4-methyl-2-oxazolyl)urea

HRID 46756

反応式

HRID 46756 の反応式
[CH2:1]([NH:5][C:6]1[O:7][CH:8]=[C:9]([CH3:11])[N:10]=1)[CH2:2][CH2:3][CH3:4].[CH2:12]([N:18]=[C:19]=[O:20])[CH2:13][CH2:14][CH2:15][CH2:16][CH3:17]>C1C=CC=CC=1>[CH2:1]([N:5]([C:6]1[O:7][CH:8]=[C:9]([CH3:11])[N:10]=1)[C:19]([NH:18][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])=[O:20])[CH2:2][CH2:3][CH3:4]

参加物

4

反応物 2

HCID 75659Hexyl isocyanateHCID 122952262-Oxazolamine, N-butyl-4-methyl-

生成物 1

HCID 234689651-Butyl-3-hexyl-1-(4-methyl-2-oxazolyl)urea

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

A solution of 2-butylamino-4-methyloxazole (10.0 g, 0.065 mol) and hexyl isocyanate (8.25 g, 0.065 mol) in dry benzene was heated under reflux for 3 hours. The solution was evaporated and the residual oil dissolved in ether, washed with dilute HCl, dried and re-evaporated. The residue was dissolved in petroleum spirit (40°-60° C.) carbon treated and re-evaporated under vacuum to give the pure product as a pale oil.

後処理

  1. temperatureunder reflux for 3 hours
  2. customThe solution was evaporated
  3. dissolutionthe residual oil dissolved in ether
  4. washwashed with dilute HCl
  5. customdried
  6. customre-evaporated
  7. dissolutionThe residue was dissolved in petroleum spirit (40°-60° C.) carbon
  8. additiontreated
  9. customre-evaporated under vacuum

出典と根拠

ORDレコード
ord-2bc3d766393b4ebd9c950080f5bf1a4b
出典データセット
uspto-grants-1979_11
特許番号
US04175131

関連ノート

読み込み中…