3-Aminopicolinic acid → 3-Amino-N-(2-methoxyethyl)-N-methylpicolinamide

反応式

[NH2:1][C:2]1[C:3]([C:8]([OH:10])=O)=[N:4][CH:5]=[CH:6][CH:7]=1.[CH3:11][O:12][CH2:13][CH2:14][NH:15][CH3:16]>>[NH2:1][C:2]1[C:3]([C:8]([N:15]([CH2:14][CH2:13][O:12][CH3:11])[CH3:16])=[O:10])=[N:4][CH:5]=[CH:6][CH:7]=1

参加物

反応物 2

HCID 738363-Aminopicolinic acid

HCID 300977(2-Methoxyethyl)(methyl)amine

生成物 1

HCID 700969433-Amino-N-(2-methoxyethyl)-N-methylpicolinamide収率 85%

実験手順

According to the procedure described in example 29, 3-aminopicolinic acid was reacted with 2-methoxy-N-methylethanamine to give the title compound (85%) as colourless viscous oil.

出典と根拠

ORDレコード: ord-e2722df999c1485383d3111e2f5a26db
出典データセット: uspto-grants-2014_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08623866B2

反応ノート

読み込み中…