関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | 2-(3,4-Dimethoxyphenyl)-N-(2-phenylethyl)ethan-1-amine--hydrogen bromide (1/1) | HCID 3048686 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | AN-465/43411221 | HCID 215356 | 97.5% |
反応手順
25 g of the latter hydrobromide were dissolved in 250 ml of hot water and the solution was cooled to 0° C. and made alkaline with 40 ml of 2 N sodium hydroxide. The mixture was extracted 3 times with 100 ml of ethyl acetate and the organic extracts were washed with water until the wash water had a pH of 7 to 8. The extracts were dried over sodium sulfate, were filtered and evaporated to dryness under reduced pressure to obtain 19 g of N-phenethyl-3,4-dimethoxyphenethylamine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04175136 |
|---|
| 出典データセット | uspto-grants-1979_11 |
|---|
| ORD ID | ord-667f98f9fa514bd293cae9b10b6fc01d |
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| 出典メモ | uspto-grants-1979_11 |
|---|
