関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Piperidine | HCID 8082 | — |
| 反応物 | 2-Methyl-3-buten-2-ol | HCID 8257 | — |
| 反応物 | 2-Bromopropene | HCID 11202 | — |
| 反応物 | Triphenylphosphine | HCID 11776 | — |
| 触媒 | palladium(II) acetate | HCID 167845 | — |
| 生成物 | 2,5-Dimethyl-6-piperidinohex-4-en-2-ol | HCID 54073601 | 80% |
反応手順
A mixture of 10 mmoles 2-bromopropene, 12.5 mmoles 2-methyl-3-buten-2-ol, 30 mmoles piperidine, 0.10 mmole palladium acetate and 0.20 mmole triphenylphosphine were heated together at 100° C. for 20 hrs. From the reaction mixture there was isolated an 80% yield of 2,5-dimethyl-6-piperidinohex-4-en-2-ol.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04175187 |
|---|
| 出典データセット | uspto-grants-1979_11 |
|---|
| ORD ID | ord-36b3dc7de3a744b7b84c6924ec4ae3cb |
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| 出典メモ | uspto-grants-1979_11 |
|---|
