化工社化工社 化学情報印刷レポート · 研究参考用
Fluprostenol → HCID 178459549、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Fluprostenol | HCID 5311100 | — |
| 反応物 | HCID 178418600 | HCID 178418600 | — |
| 溶媒 | Methanol--water (1/1) | HCID 22242641 | — |
| 生成物 | HCID 178459549 | HCID 178459549 | — |
反応手順
To travoprost free acid ((+)-fluprostenol free acid) 3 in MeOH/H2O was added L-Arginine (>98%) (Sigma-Aldrich Cat. A5006) and the solution was stirred for 30 minutes. The solvents were evaporated then azeotroped with Et2O and hexanes to give white crystalline travoprost-L-Arginine salt 4 (quantitative).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08623918B2 |
| 出典データセット | uspto-grants-2014_01 |
| ORD ID | ord-62aebbbdd09a41f4866fa8fbcec861cb |
| 出典メモ | uspto-grants-2014_01 |