3-Amino-1-propanol → 3-[(2-Chloro-6-nitrophenyl)amino]-1-propanol
反応式
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([N+:8]([O-:10])=[O:9])[C:3]=1Cl.[NH2:12][CH2:13][CH2:14][CH2:15][OH:16]>C(O)CCC>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([N+:8]([O-:10])=[O:9])[C:3]=1[NH:12][CH2:13][CH2:14][CH2:15][OH:16]参加物
4
実験手順
A mixture of 100 parts of 1,2-dichloro-3-nitrobenzene, 95 parts of 3-amino-1-propanol and 200 parts of butanol is stirred and refluxed overnight. The reaction mixture is cooled and evaporated. The residue is taken up in water and the product is extracted with methylbenzene. The extract is washed with water, dried, filtered and evaporated, yielding 115 parts of 3-[(2-chloro-6-nitrophenyl)amino]-1-propanol as a residue.
後処理
- temperaturerefluxed overnight
- temperatureThe reaction mixture is cooled
- customevaporated
- extractionthe product is extracted with methylbenzene
- washThe extract is washed with water
- customdried
- filtrationfiltered
- customevaporated
出典と根拠
- ORDレコード
- ord-3cf7f60be5d04e27a25f57e8e5833753
- 出典データセット
- uspto-grants-1979_11
- 特許番号
- US04175129
反応ノート
読み込み中…