化工社化工社 化学情報印刷レポート · 研究参考用
Methanethiol → Ethyl 2-[(methylsulfanyl)methyl]prop-2-enoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanethiol | HCID 878 | — |
| 反応物 | 2-(Bromomethyl)acrylic acid ethyl ester | HCID 310620 | — |
| 反応物 | Sodium | HCID 5360545 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Ethyl 2-[(methylsulfanyl)methyl]prop-2-enoate | HCID 12463627 | — |
反応手順
A solution of methylmercaptan (4.8 g.) and sodium (2.3 g.) in absolute ethanol (75 ml.) is added dropwise to a solution of ethyl-2-bromomethylacrylate (19.3 g.) in ethanol (25 ml.). After two hours, it is diluted with water (400 ml.) and extracted with methylene chloride. The organic layer is dried and concentrated to dryness in vacuo to yield ethyl-2-methylthiomethylacrylate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04175199 |
| 出典データセット | uspto-grants-1979_11 |
| ORD ID | ord-ef169ab13b9c4ed390f40d30a51c76c2 |
| 出典メモ | uspto-grants-1979_11 |