L-Proline 1,1-dimethylethyl ester → (2-(Acetylthiomethyl)-5-oxo-6-methylheptanoyl]-L-proline tert.butyl ester
反応式
[C:1]([S:4][CH2:5][CH:6]([CH2:10][CH2:11][C:12](=[O:16])[CH:13]([CH3:15])[CH3:14])[C:7]([OH:9])=O)(=[O:3])[CH3:2].C(SCC(CC(=O)C)C(O)=S)(=O)C.[C:30]([O:34][C:35](=[O:41])[C@@H:36]1[CH2:40][CH2:39][CH2:38][NH:37]1)([CH3:33])([CH3:32])[CH3:31]>>[C:30]([O:34][C:35](=[O:41])[C@@H:36]1[CH2:40][CH2:39][CH2:38][N:37]1[C:7](=[O:9])[CH:6]([CH2:5][S:4][C:1](=[O:3])[CH3:2])[CH2:10][CH2:11][C:12](=[O:16])[CH:13]([CH3:15])[CH3:14])([CH3:33])([CH3:31])[CH3:32]参加物
4
実験手順
By substituting 2-acetylthiomethyl-5-oxo-6-methylheptanoic acid for the 2-(acetylthiomethyl)-3-acetylthiopropanoic acid in the procedure of Example 2, 1-[2-acetylthiomethyl)-5-oxo-6-methylheptanoyl]-L-proline tert.butyl ester is obtained.
後処理
- custom