Ammonia → 7-methoxy-3-{1-[6-(7-methyl-1H-indazole-5-carbonyl)-pyrimidin-4-yl]-piperidin-4-yl}-1,3,4,5-tetrahydro-benzo[d][1,3]diazepin-2-one

反応式

[CH3:1][O:2][C:3]1[CH:46]=[CH:45][C:6]2[NH:7][C:8](=[O:44])[N:9]([CH:12]3[CH2:17][CH2:16][N:15]([C:18]4[CH:23]=[C:22]([C:24]([C:26]5[CH:27]=[C:28]6[C:32](=[C:33]([CH3:35])[CH:34]=5)[N:31](COCC[Si](C)(C)C)[N:30]=[CH:29]6)=[O:25])[N:21]=[CH:20][N:19]=4)[CH2:14][CH2:13]3)[CH2:10][CH2:11][C:5]=2[CH:4]=1.Cl.N.O>CO.O1CCOCC1>[CH3:1][O:2][C:3]1[CH:46]=[CH:45][C:6]2[NH:7][C:8](=[O:44])[N:9]([CH:12]3[CH2:17][CH2:16][N:15]([C:18]4[CH:23]=[C:22]([C:24]([C:26]5[CH:27]=[C:28]6[C:32](=[C:33]([CH3:35])[CH:34]=5)[NH:31][N:30]=[CH:29]6)=[O:25])[N:21]=[CH:20][N:19]=4)[CH2:14][CH2:13]3)[CH2:10][CH2:11][C:5]=2[CH:4]=1